Dissemination
PublicationsIn books or monographsCabral JMS, da Silva CL (Eds.) “Bioreactors for Stem Cell Expansion and Differentiation”. CRC Press, ISBN 9780367732936 (2020). Fonseca AC, Ferro JM (Eds.) “Precision Medicine in Stroke”. Springer Nature, in press (2021) In chapters of booksRodrigues CAV, Nogueira DES, Branco M, Silva TP, Gomes AR, Diogo MM, Cabral JMS, “Bioreactors for Human Pluripotent Stem Cell Expansion and Differentiation”, in “Bioreactors for Stem Cell Expansion and Differentiation”, Cabral, J.M.S., Lobato da Silva, C. (ed.), Taylor & Francis, pp. 25-45 (2020). Costa MHG, Ferreira FC, Cabral JMS, da Silva CL “Bioreactors for the cultivation of hematopoietic stem and progenitor cells” in “Bioreactors for Stem Cell Expansion and Differentiation”, Cabral JMS, da Silva CL (Eds.), Taylor & Francis, pp. 165-200 (2020). https://dx.doi.org/10.1201/9780429453144-7. Miranda CC, Fernandes TG, Diogo MM, Cabral JMS, “Human Pluripotent Stem Cells: Applications and Challenges for Regenerative Medicine and Disease Modeling”, In Adv. Biochem Eng Biotechnol, 171:189-224 (2020). https://dx.doi.org/10.1007/10_2019_117. de Almeida Fuzeta, Miguel; de Matos Branco, André Dargen; FernandesPlatzgummer, Ana; da Silva, Cláudia Lobato; Cabral, Joaquim M. S. 2019. “Addressing the Manufacturing Challenges of Cell-Based Therapies”. In Adv. Biochem Eng Biotechnol, 171:225-278 (2020). https://dx.doi.org/10.1007/10_2019_118. Fernandes-Platzgummer, Ana; Andrade, Pedro; Cabral, Joaquim M. S.; Lobato da Silva, C. “Scalable manufacturing of hematopoietic stem/progenitor cells exploiting a co-culture platform with mesenchymal stromal cells.” In Methods Mol Biol https://dx.doi.org/10.1007/7651_2020_289. (2020) Carmo-Fonseca M. Precision Medicine: enabling healthcare progress in the twenty-first century. In Fonseca AC, Ferro JM (Eds.) “Precision Medicine in Stroke”. Springer Nature (in press) (2021) In scientific magazines Irene Gullo* , Catarina Costa, Susana L. Silva*, Cristina Ferreira, Adriana Motta, Sara P. Silva, Rúben Duarte Ferreira, Pedro Rosmaninho, Emília Faria, José Torres da Costa, Rita Câmara, Gilza Gonçalves, João Santos-Antunes, Carla Oliveira, José C. Machado, Fátima Carneiro, and Ana E. Sousa, “The Dysfunctional Immune System in Common Variable Immunodeficiency Increases the Susceptibility to Gastric Cancer”, Cells, 19 June 2020, Cells 2020, 9(6), 1498; 10.3390/cells9061498 J. A. Carriço, M. Crochemore, A. P. Francisco, S. P. Pissis, B. Ribeiro-Gonçalves and C. Vaz. “Fast phylogenetic inference from typing data.” Algorithms for Molecular Biology, 13:4, 2018. https://doi.org/10.1186/s13015-017-0119-7 A. S. Teixeira, P. T. Monteiro, J. A. Carriço and A. P. Francisco. “Large-scale simulations of bacterial populations over complex networks.” Journal of Computational Biology, 25(8), 2018. https://doi.org/10.1089/cmb.2018.0083 Silveira C*, Sousa AC*, Janeiro A*, Malveiro S, Teixeira E, Brysch E, Pantarotto M, Felizardo M, Madureira R, Nogueira F, Guimarães C, Matos C, Canário D, Bruges-Armas J, Carmo-Fonseca M Detection and quantification of EGFR T790M mutation in liquid biopsies by droplet digital PCR. Translational Lung Cancer Research (2020). doi: 10.21037/tlcr-20-1010. António Sousa‐Franco, Kenny Rebelo, Simão Teixeira da Rocha, Bruno Bernardes de Jesus. “LncRNAs regulating stemness in aging” Aging Cell, 18(1):e1287020 (2019) https://doi.org/10.1111/acel.12870. Desterro J, Bak-Gordon P, Carmo-Fonseca M. Targeting mRNA processing as an anticancer strategy. Nature Reviews Drug Discovery (2019) doi: 10.1038/s41573-019-0042-3. Prudêncio P, Rebelo K, Grosso AR, Martinho RG, Carmo-Fonseca M. Analysis of mammalian native elongating transcript sequencing (mNET-seq) high-throughput data. Methods (2019) doi: 10.1016/j.ymeth.2019.09.003. Mendes de Almeida R, Tavares J, Martins S, Carvalho T, Enguita FJ, Brito D, Carmo-Fonseca M, Lopes LR. “Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy.” Plos One 12(8):e0182946. (2017) doi: 10.1371/journal.pone.0182946. Ribeiro M, Furtado M, Martins S, Carvalho T, Carmo-Fonseca M RNA splicing defects in hypertrophic cardiomyopathy: implications for diagnosis and therapy. Int J Mol Sci 21(4):1329. (2020) doi: 10.3390/ijms21041329. Gisela S. Gordino, Sara Costa-Pereira, Patrícia Corredeira, Patrícia B. Alves, Luís M. Costa, Anita Q. Gomes, Bruno Silva-Santos and Julie C. Ribot. MicroRNA-181a Restricts Human γδ T Cell Functional Differentiation by Targeting Map3k2 and Notch2. Under review (EMBO Rep). Fonseca AC, Alves P, Inácio N, Marto JP, Viana-Baptista M, Pinho-E-Melo T, Ferro JM, Almeida AG. “Patients With Undetermined Stroke Have Increased Atrial Fibrosis: A Cardiac Magnetic Resonance Imaging Study”. Stroke 49:734-737 (2018). doi: 10.1161/STROKEAHA.117.019641. Miguel Monteiro, Ana Catarina Fonseca, Ana Teresa Freitas, Teresa Pinho e Melo, Alexandre P. Francisco, José M. Ferro, Arlindo L. Oliveira. Using Machine Learning to Improve the Prediction of Functional Outcome in Ischemic Stroke Patients. IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB) Special issue”. doi: 10.1109/TCBB.2018.2811471. Fonseca AC, Marto JP, Pimenta D, Guimarães T, Alves PN, Inácio N, Viana-Baptista M, Pinho E Melo T, Pinto FJ, Ferro JM, Almeida AG. Undetermined stroke genesis and hidden cardiomyopathies determined by cardiac magnetic resonance. Neurology 94:e107-e113 (2020). doi: 10.1212/WNL.0000000000008698. Miguel Monteiro, Ana Catarina Fonseca, Ana Teresa Freitas, Teresa Pinho E Melo, Alexandre P Francisco, José M Ferro and Arlindo Oliveira. “Improving the Prediction of Functional Outcome in Ischemic Stroke Patients.” In Workshops on Data Mining in Bioinformatics (BIOKDD) 2018, ACM SIGKDD. https://www.inesc-id.pt/ficheiros/publicacoes/13254.pdf Miguel Monteiro, Mário A. T. Figueiredo, Arlindo L. Oliveira, “Conditional Random Fields as Recurrent Neural Networks for 3D Medical Imaging Segmentation”, in MED-NEURIPS 2018, https://www.inesc-id.pt/ficheiros/publicacoes/14380.pdf Rodrigues CAV, Nogueira DES, Cabral JMS, “Next-Generation Stem Cell Expansion Technologies”, Cell Gene Therapy Insights 4(8):791-804 (2018) https://doi.org/10.18609/cgti.2018.076 Ferro T, Santhagunam A, Madeira C, Salgueiro JB, da Silva CL, Cabral JMS “Successful isolation and ex vivo expansion of human mesenchymal stem/stromal cells obtained from different synovial tissue-derived (biopsy) samples”, J Cell Physiol. 234: 3973-3984 (2019) doi: 10.1002/jcp.27202. Rodrigues AL, Rodrigues CAV, Gomes AR, Vieira SF, Badenes SM, Diogo MM, Cabral JMS “Dissolvable Microcarriers Allow Scalable Expansion And Harvesting Of Human Induced Pluripotent Stem Cells Under Xeno‐Free Conditions”, Biotechnology Journal 14:e1800461 (2019) DOI:10.1002/biot.201800461 Silva TP, Cotovio JP, Bekman E, Carmo-Fonseca M, Cabral JMS, Fernandes TG. Design principles for pluripotent stem cell-derived organoid engineering. Stem Cells International (2019) Silva JC, Moura CS, Borrecho G, de Matos APA, da Silva CL, Cabral JC, Bártolo PL, Linhardt RJ, Ferreira FC, Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly(ɛ‐Caprolactone) Scaffolds. Biotechnol. J. 15:1900078 (2019). https://doi.org/10.1002/biot.201900078 Garrudo FF, Udangawa RW, Hoffman P, Sordini L, Chapman CA, Mikael PE, Ferreira FA, Silva JC, Rodrigues CAV, Cabral JMS, Morgado JMF, Ferreira FC, Linhardt RJ, Polybenzimidazole nanofibers for neural stem cell culture, Materials Today Chemistry, 14:100185 (2019) https://doi.org/10.1016/j.mtchem.2019.08.004 Branco MA, Cotovio JP, Rodrigues CAV, Vaz SH, Fernandes TG, Moreira LM, Cabral JMS Cabral, Diogo MM, Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture, Scientific Reports, 9:9229, (2019). doi: 10.1038/s41598-019-45047-9. Garrudo FF, Chapman CA, Hoffman P, Udangawa RN, Silva JC, Mikael PE, Rodrigues CAV, Cabral JMS, Morgado JMF, Ferreira FC, Linhardt RJ, Polyaniline-polycaprolactone blended nanofibers for neural cell culture, European Polymer Journal, 117:28-37 (2019). doi: 10.1016/j.eurpolymj.2019.04.048 Silva TP, Bekman EP, Fernandes TG, Vaz SH, Rodrigues CAV, Diogo MM, Cabral JMS, Carmo-Fonseca M, “Maturation of Human Pluripotent Stem Cell-Derived Cerebellar Neurons in the Absence of Co-culture”, Front Bioeng Biotechnol, 8:70 (2020). doi: 10.3389/fbioe.2020.00070. Amores de Sousa MC, Rodrigues CAV, Ferreira IAF, Diogo MM, Linhardt RJ, Cabral JMS, Ferreira FC, Functionalization of electrospun nanofibers and fiber alignment enhance neural stem cell proliferation and neuronal differentiation, Frontiers in Bioengineering and Biotechnology (2020) https://doi.org/10.3389/fbioe.2020.580135 C. S. Moura, J. C. Silva, S. P. Faria, P. R. Fernandes, C. L. da Silva, J. M. S. Cabral, P. J. Bártolo, F. C. Ferreira, “Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: effects of material alkaline treatment and chondroitin sulfate supplementation”. Journal Bioscience Bioengineering 129: 756-764 (2020). https://doi.org/10.1016/j.jbiosc.2020.01.004. Silva JC, Han C, Silva TP, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ, “Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow−/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia” Glycoconj J 37:345–360 (2020). https://doi.org/10.1007/s10719-020-09911-5. Silva JS, Carvalho MS, Udangawa RN, Moura CS, Cabral JMS, da Silva CL, Ferreira FC, Vashishth D, Linhardt RJ, Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient‐tailored bone tissue engineering approach, J Biomed Mater Res B Appl Biomater 108:2153-2166 (2020). https://doi.org/10.1002/jbm.b.34554 Silva JS, Moura CS, Borrecho G, de Matos APA, Cabral JMS, Linhardt R, Ferreira FCF, Effects of glycosaminoglycan supplementation in the chondrogenic differentiation of bone marrow- and synovial- derived mesenchymal stem/stromal cells on 3D-extruded poly (ε-caprolactone) scaffolds. International Journal of Polymeric Materials and Polymeric Biomaterials. 70: 1-16 (2020) https://doi.org/10.1080/00914037.2019.1706511. Figueiredo L, Fonseca R, Pinto LVF, Ferreira FC, Almeida MA, Rodrigues A, Strategy to improve the mechanical properties of bioabsorbable materials based on chitosan for orthopedic fixation applications, J Mech Behav Biomed 103: 103572 (2020) https://doi.org/10.1016/j.jmbbm.2019.103572 Silva JC, Udangeawa RN, Chen J, Mancinelli CD, Garrudo FF, Mikael PE, Cabral JMS, Ferreira FC Linhardt RJ, “Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering” Mater Sci Eng C. 107: 110234 (2020). doi: 10.1016/j.msec.2019.110291. Garrudo FFF, Mikael PE, Rodrigues CAV, Udangawa RW, Paradiso P, Chapman CA, Hoffman P, Colaço R, Cabral JMS, Morgado J, Linhardt RJ, Ferreira FC, Polyaniline-polycaprolactone fibers for neural applications: electroconductivity enhanced by pseudo-doping, Materials Science and Engineering: C 120: 111680 (2021). https://doi.org/10.1016/j.msec.2020.111680 Costa MHG, Soure AM, Cabral JMS, Ferreira FC, da Silva CL. “Hematopoietic niche – exploring biomimetic cues to improve the functionality of Hematopoietic Stem/Progenitor Cells.” Biotechnol. J. (2018). doi: 10.1002/biot.201700088. Cabral JMS, Palecek SP, “Regenerative Medicine Manufacturing”. Biotechnol J (2018) doi: 10.1002/biot.201800026. Mizukami A, Neto MSA, Moreira F, Fernandes-Platzgummer A, Huang YF, Milligan W, Cabral JMS, da Silva CL, Covas DT, Swiecha K. “A fully-closed and automated hollow fiber bioreactor for clinical-grade manufacturing of human mesenchymal stem/stromal cells”, Stem Cell Reviews and Reports. 14:141-143 (2018) doi: 10.1007/s12015-017-9787-4. Bandeiras C, Cabral JMS, Finkelstein SN, Ferreira FC “Modeling biological and economic uncertainty on cell therapy manufacturing: the choice of culture media supplementation”, Regenerative Medicine 13:917-933 (2018). doi: 10.2217/rme-2018-0034. Serra J, Alves CPA, Brito L, Monteiro GA, Cabral JMS, Prazeres DMF, da Silva CL “Engineering of Human Mesenchymal Stem/Stromal Cells with Vascular Endothelial Growth Factor-Encoding Minicircles for Angiogenic Ex Vivo Gene Therapy”, Hum Gene Ther. 30:316-329 (2019) doi: 10.1089/hum.2018.154. Pinto DS, Bandeiras C, Fuzeta MA, Rodrigues CAV, Jung S, Hashimura Y, Tseng RJ, Milligan W, Lee B, Ferreira FC, da Silva CL, Cabral JMS. “Scalable Manufacturing of Human Mesenchymal Stromal Cells in the Vertical-Wheel Bioreactor System: An Experimental and Economic Approach”. Biotechnol J. (2019) doi: 10.1002/biot.201800716. Bandeiras C, Hwa A, Cabral JMS, Ferreira FC, Finkelstein SN, Gabbay RA, Economics of Beta-Cell Replacement Therapy, Curr Diab Rep. 75 (2019). doi: 10.1007/s11892-019-1203-9. Bandeiras C., Cabral JMS, Gabbay RA, Finkelstein SN, Ferreira FC, “Bringing Stem Cell-Based Therapies for Type 1 Diabetes to the Clinic: Early Insights from Bioprocess Economics and Cost-Effectiveness Analysis” Biotechnol J. 14:1800563 (2019) doi: 10.1002/biot.201800563 Azevedo RI, Minskaia E, Fernandes-Platzgummer A, Vieira AIS, da Silva CL, Cabral JMS, Lacerda JF. Mesenchymal stromal cells induce regulatory T cells via epigenetic conversion of human conventional CD4 T cells in vitro. Stem Cells 38:1007-1019 (2020). doi: 10.1002/stem.3185. Fuzeta MA, Bernardes N, Oliveira FD, Costa AC, Fernandes-Platzgummer A, Farinha JP, Rodrigues CAV, Jung S, Tseng RJ, Milligan W, Lee B, Castanho M, Gaspar D, Cabral JMS, da Silva CL. “Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System”. Front. Dev. Bio. (2020) doi: 10.3389/fcell.2020.553444. Pinto DS; Ahsan T; Serra J; Fernandes-Platzgummer A; Cabral JMS; da Silva CL. “Modulation of the in vitro angiogenic potential of human mesenchymal stromal cells from different tissue sources.”. Journal of cellular physiology. 235:7224-7238 (2020). https://doi.org/10.1002/jcp.29622 Branco A, Bucar S, Moura-Sampaio J, Lilaia C, Cabral JMS, Fernandes-Platzgummer A and Lobato da Silva C. “Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells”. Front. Bioeng. Biotechnol. 8:573282 (2020) doi: 10.3389/fbioe.2020.573282 Caiado F, Maia-Silva D, Jardim C, Schmolka N, Carvalho T, Reforço C, Faria R, Kolundzija B, Simões AE, Baubec T, Vakoc CR, da Silva MG, Manz MG, Schumacher TN, Norell H, Silva-Santos B. Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection. Nature Communications 10(1):4986 (2019). doi: 10.1038/s41467-019-12983-z. Di Lorenzo B, Ravens S, Silva-Santos B. High-throughput analysis of the human thymic Vδ1+ T cell receptor repertoire. Scientific Data 6(1):115 (2019). doi: 10.1038/s41597-019-0118-2. Mikulak J, Oriolo F, Bruni E, Roberto A, Colombo FS, Villa A, Bosticardo M, Bortolomai I, Lo Presti E, Meraviglia S, Dieli F, Vetrano S, Danese S, Della Bella S, Carvello MM, Sacchi M, Cugini G, Colombo G, Klinger M, Spaggiari P, Roncalli M, Prinz I, Ravens S, di Lorenzo B, Marcenaro E, Silva-Santos B, Spinelli A, Mavilio D. NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer. Journal of Clinical Investigation Insight 4(24):e125884 (2019) doi: 10.1172/jci.insight.125884 Sebestyen Z, Prinz I, Déchanet-Merville J, Silva-Santos B, Kuball J. Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies. Nature Reviews Drug Discovery 19:169-184 (2020) https://doi.org/10.1038/s41573-019-0038-z In articles or abstracts of scientific communicationsM. Crochemore, A. P. Francisco, S. P. Pissis and C. Vaz. “Towards distance-based phylogenetic inference in average-case linear-time.” In 17th International Workshop on Algorithms in Bioinformatics (WABI 2017), Leibniz International Proceedings in Informatics (LIPIcs), 88(9):1-14, 2017. https://doi.org/10.4230/LIPIcs.WABI.2017.9 B. Dantas, C. Fleitas, A. Almeida, J. Forja, A. P. Francisco, J. Simão and C. Vaz. “NGSPipes: Fostering reproducibility and scalability in biosciences.” In Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics, 603-603, 2017. https://doi.org/10.1145/3107411.3108213 A. P. Francisco, M. Nascimento and C. Vaz. “Dynamic phylogenetic inference for sequence-based typing data.” In Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics, 604-604, 2017. https://doi.org/10.1145/3107411.3108214 A. S. Teixeira, P. T. Monteiro, J. A. Carriço, F. C. Santos and A. P. Francisco. “Using Spark and GraphX to parallelize large-scale simulations of bacterial populations over host contact networks.” In Algorithms and Architectures for Parallel Processing: 17th International Conference, ICA3PP 2017, 591-600, 2017. https://doi.org/10.1007/978-3-319-65482-9_44 |
CommunicationsIn international events1- Maria Margarida Diogo, “Xeno-free production and recovery of human pluripotent stem cells using synthetic dissolvable microcarriers”, Scale-up and Manufacturing of Cell-based Therapies V, San Diego, CA, USA, January 15-19, 2017. 2- Fernandes-Platzgummer A, “Scalable production of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems”, 1st Stem Cell Community Day, organized by Eppendorf, Hamburg, Germany, April 4, 2017. 3- J. C. Silva, R. N. Udangawa, F. F. Garrudo, P.E. Mikael, F. C. Ferreira, R. J. Linhardt “Biodegradable aligned core-shell nanofibers for articular cartilage tissue engineering”, oral presentation by J. C. Silva at 254th ACS National Meeting in Washington, DC, August 20-24, 2017. 4- F. F. F. Garrudo, J.C.F. Silva, C.A.V. Rodrigues, J.M.F. Morgado, R.J. Linhardt, F.C. Ferreira, “Polybenzimidazole electrospun nanofibers for neural cell culture”, oral presention by F. F. F. Garrudo at 254th ACS National Meeting in Washington, DC, August 20-24, 2017. 5- M. Fonseca, A. Serra-Caetano, R.R. Barbosa, S.P. Silva, L. Hammarstrom, M. Cascalho, S.L. Silva, A.E. Sousa, “Novel TACI variant in Common Variable Immunodeficiency”, European Immunodeficiencies (ESID) Meeting 2017, Edinburgh, UK, September 2017. 6- Y. Tokuanga, H. Nunes-Cabaço, A.E. Sousa, “Differentiation of FOXP3+ regulatory T cells in the human thymus: unbiased approaches circumventing sequential-gating strategy”, 7th International Workshop of Kyoto T cell Conference, a Global Thymus Network meeting KTCC2017, Kyoto, Japan, March 2017. 7- A. Ramalho-dos-Santos, L. Martins, J. Barata, A. E. Sousa, H. Nunes-Cabaço, “IL-4 induces coreceptor reversal in CD4-committed human thymocytes”, 7th International Workshop of Kyoto T cell Conference, a Global Thymus Network meeting KTCC2017, Kyoto, Japan, March 2017. 8- M. Crochemore, A. P. Francisco, S. P. Pissis and C. Vaz. “Towards distance-based phylogenetic inference in average-case linear-time.” In 17th International Workshop on Algorithms in Bioinformatics (WABI 2017), Leibniz International Proceedings in Informatics (LIPIcs), 88(9):1-14, 2017. https://doi.org/10.4230/LIPIcs.WABI.2017.9 9- B. Dantas, C. Fleitas, A. Almeida, J. Forja, A. P. Francisco, J. Simão and C. Vaz. “NGSPipes: Fostering reproducibility and scalability in biosciences.” In Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics, 603-603, 2017. https://doi.org/10.1145/3107411.3108213 10- A. P. Francisco, M. Nascimento and C. Vaz. “Dynamic phylogenetic inference for sequence-based typing data.” In Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics, 604-604, 2017. https://doi.org/10.1145/3107411.3108214 11- A. S. Teixeira, P. T. Monteiro, J. A. Carriço, F. C. Santos and A. P. Francisco. “Using Spark and GraphX to parallelize large-scale simulations of bacterial populations over host contact networks.” In Algorithms and Architectures for Parallel Processing: 17th International Conference, ICA3PP 2017, 591-600, 2017. https://doi.org/10.1007/978-3-319-65482-9_44 12- Miguel Monteiro, Ana Catarina Fonseca, Ana Teresa Freitas, Teresa Pinho E Melo, Alexandre P Francisco, José M Ferro and Arlindo Oliveira. “Improving the Prediction of Functional Outcome in Ischemic Stroke Patients.” In Workshops on Data Mining in Bioinformatics (BIOKDD) 2018, ACM SIGKDD. https://www.inesc-id.pt/ficheiros/publicacoes/13254.pdf 13- Rodrigues CAV, Fernandes TG, Giroux D, Hashimura Y, Wesselschmidt R, Diogo MM, Lee B, Cabral JMS, “Development Of A Scale-Down Approach To The Scalable Culture Of Induced Pluripotent Stem Cells On Microcarriers Using Single-Use Vertical-Wheel Bioreactors Under Xeno-Free Conditions”, Scale-up and Manufacturing of Cell-Based Therapies IV, San Diego, CA USA, January 15-18, 2017. 14- Fernandes-Platzgummer A, De Soure AM, Huang Y-F, Milligan W, Mizukami A, Swiech K, Silva CL, Cabral JMS, “Umbilical cord matrix derived-mesenchymal stem/stromal cell production in microcarrier-based culture systems”, Scale-up and Manufacturing of Cell-Based Therapies IV, San Diego, CA USA, January 15-18, 2017. 15- Rodrigues CAV, Silva TP, Fernandes TG, Hashimura Y, Wesselschmidt R, Diogo MM, Lee B, Cabral JMS, “Scalable culture of induced pluripotent cells on microcarriers under xeno-free conditions using single-use vertical-wheel™ bioreactors”, 1st Stem Cell Community Day, Organized by Eppendorf, Hamburg, Germany, April 4, 2017. 16- Bear MM, Hervy M, Henry D, Weber JL, Scibek J, Roosloot R, Das R , Vieira SFV, Rodrigues AL, Rodrigues CAV, Badenes SM, Diogo MM, Cabral JMS, Zhou Y, “Dissolvable Microcarriers For Efficient Cell Production And Recovery”, Bioprocessing of Advanced Cellular Therapies Congress, London, UK, June 8-9, 2017. 17- Bear MM, Hervy M, Henry D, Weber JL, Scibek J, Roosloot R, Das R , Vieira SFV, Rodrigues AL, Rodrigues CAV, Badenes SM, Diogo MM, Cabral JMS, Zhou Y, “Dissolvable Microcarriers For Efficient Cell Production And Recovery”, International Society For Stem Cell Research Annual Meeting, Boston, USA, June 14-17, 2017. 18- J. C. Silva, C. S. Moura, G. Borrecho, A.P.A. de Matos, J. M. S. Cabral, R. J. Linhardt, F. C. Ferreira, “Effects of chondroitin sulfate and hyaluronic acid supplementation in the chondrogenic differentiation of bone marrow/synovial – derived mesenchymal stem cells on poly (ε-caprolactone) scaffolds towards cartilage repair”, poster presentation by J. C. Silva at 254th ACS National Meeting in Washington, DC, August 20-24, 2017. 19- F.F.F. Garrudo, J.C.F. Silva, P.E. Mikael, F.C. Ferreira, R.J. Linhardt, “Glycosaminoglycan change in differentiating ReN cells”, Poster presention by F. F. F. Garrudo at 254th American Chemical Society National Meeting & Exposition, Washington, DC, August 20-24, 2017. 20- Silveira C, Sousa AC, Janeiro A, Felizardo M, Carmo-Fonseca M; “ddPCR to detect EGFR T790M”; Liquid Biopsies EMBL Course, EMBL Heidelberg, Germany, 09-13 October 2017. 21- Silva, T.P., Bekman, E., Fernandes, T.G., Rodrigues, C.A.V., Diogo, M.M., Cabral, J.M.S., Carmo-Fonseca, M., “Cerebellar differentiation and maturation from Human Induced Pluripotent Stem Cells”, International Society for Stem Cell Research, Annual Meeting, Boston, USA, June 14-17, 2017. 22- Bernardes de Jesus B, Marinho SP, Sousa-Franco A, Alves-Vale C, Carvalho T, Carmo-Fonseca M. Silencing the long non-coding RNA antisense to Zeb2 facilitates reprogramming of aged fibroblasts and safeguards stem cell pluripotency Poster presented by Bruno Bernardes de Jesus at the Stem Cell Biology Meeting, CSH, NY, 25-29 September 2017. 23- M.R. Matos, I. Posa, F. Carvalho, V. Morais, A.R. Grosso, S.F. Almeida “A systematic pan-cancer analysis of somatic variants reveals epigenetic drivers of intratumor heterogeneity”. Talk presented at Cell Symposia: TCGA Legacy, Multi-Omics Studies in Cancer, September 27-29, 2018. Washington DC, USA 24- Luís Costa, “Liquid Biopsy in Advanced Breast Cancer: Ready for Prime time or work in Progress?”, VI Congresso Internacional Oncologia D’OR, Rio de Janeiro, Brasil, November 9-10, 2018 25- Luís Costa, “What have we learned so far?”, III Simposio Biopsia Líquida – El camino a la Oncología de Precisión, Santiago de Compostela, Spain, January 25-27, 2018 26- Patrícia Corredeira, Patrícia Martins, Pedro Andrade, André Mansinho, Arlindo Ferreira, Sandra Casimiro, Julie Ribot, Bruno Silva-Santos, Lorena Dieguez, Luis Costa, “Oncodynamics Liquid Biobanking: A holistic perspective towards predictive medicine in metastatic cancer” III Simposio Biopsia Líquida – El camino a la Oncología de Precisión, Santiago de Compostela, Spain, January 25-27, 2018 27- Ângelo-Dias M, Godinho-Santos A, Tokunaga Y, Serra-Caetano A, Nunes-Cabaço H, Sousa AE, Raposo AASF. Uncovering the regulatory T cell transcriptional signature in the human thymus. 5th European Congress of Immunology (ECI 2018), Amsterdam, Netherlands, 2-5 September 2018 (oral presentation) 28- Ângelo-Dias M, Godinho-Santos A, Tokunaga Y, Serra-Caetano A, Nunes-Cabaço H, Sousa AE, Raposo AASF. Transcriptional Signature of Thymic-committed Human Regulatory T-cells. 18th Biennial Meeting of the European Society for Immunodeficiencies (ESID 2018), Lisbon, Portugal, 24-27 October 2018 (oral presentation) 29- Rosmaninho P, Raposo AASF, Abolhassani H, Hammarström L, Sousa AE, Silva SL. Mining the multigenic landscape underlying Common Variable Immunodeficiency Disorders. 18th Biennial Meeting of the European Society for Immunodeficiencies (ESID 2018), Lisbon, Portugal, 24-27 October 2018 (poster) 30- Fonseca M, Serra-Caetano A, Pereira M, Silva SP, Hammarstrom L, Carvalho MG, Silva SL, Ana E Sousa AE. Polygenic burden in common variable immunodeficiency? a monozygotic twin pair study. 18th Biennial Meeting of the European Society for Immunodeficiencies (ESID 2018), Lisbon, Portugal, 24-27 October 2018 (poster) 31- Sousa AE. Lessons learned from FOXN1 deficiency. 18th Biennial Meeting of the European Society for Immunodeficiencies (ESID 2018), Lisbon, Portugal, 24-27 October 2018 (invited lecture) 32- Silva SL. Exploring the genetic basis for severe/extreme clinical phenotypes in CVID. 20th EUROFLOW-PID Meeting, Kiel, Germany, 5-6 November 2018 (invited lecture) 33- Di Lorenzo B, Simões A, Caiado F, Tieppo P, Ravens S, Correia DV, Carvalho T, Gomes Da Silva M, Norell H, Déchanet-Merville J, Prinz I, Vermijlen D, Silva-Santos B. Cytotoxic targeting of Acute Myeloid Leukemia by highly polyclonal Delta One T (DOT) cells. 8th International γδ T-Cell Conference, Bordéus (França). 7-10 de junho de 2018. (Apresentação oral selecionada dos resumos) 34- Bruno Silva-Santos. Gamma-delta T cell differentiation and cancer immunity. European Congress of Immunology. Amesterdão (Holanda), 3 de setembro de 2018. (Apresentação oral por convite) 35- Bruno Silva-Santos. Innovative cell therapy in cancer – Delta One T cells. European Society of Immunodeficiencies Meeting. Lisboa, 25 de outubro de 2018. (Apresentação oral por convite) 36- Fonseca AC, “Do we already have precision medicine in stroke?”, 4ºEuropean Congress of the European Academy of Neurology, Lisbon, Portugal, June 16-19, 2018 37- Fonseca AC, Eugénio P, Marto JP, Inácio N, Nascimento PA, Viana-Baptista M, Pinho e Melo T, Ferro JM, Almeida AG, “Evaluation of serum biomarkers related to atrial remodeling in patients with undetermined stroke etiology”. European Stroke Organisation Conference 2018, Gothenburg, Sweden, May 16-18, 2018. 38- Filipa S Carvalho, Ana C Fonseca, José M Ferro, Sofia Galego, Vanessa A Morais. Enlightening Precision Medicine: identification of mitochondrial DNA mutations on stroke patients. Kyoto, Japan – Keystone Symposia meeting on Mitochondrial Biology, April 22-26, 2018. 39- Rodrigues CAV, “Scalable microcarrier-based systems for pluripotent stem cell expansion”, 2nd Stem Cell Community Day, Dusseldorf, Germany, April 24, 2018 40- Bandeiras C, Cabral JMS, Finkelstein SN, Ferreira FC “A Bioeconomics model for bioprocessing of Pluripotent stem cells” Oral Presentation by C Bandeiras at 12th Symposium of the European Society of Biochemical Engineering Sciences, ESBES 2018. 9-12 September 2018, Lisbon, Portugal 41- Silva JC, Moura CS, Borrecho G, Matos APA, Cabral JMS, Linhardt RJ, Ferreira FC “Extruded Perfusion Bioreactors: a versatile custom-made platform to study shear stress in cartilage tissue engineered constructs” Oral Presentation by JC Silva EORS 2018-26th annual meeting Cartilage – 27th September 2018-Galway, Ireland 42- Silva JC, Moura CS, Borrecho G, Matos APA, Cabral JMS, Linhardt RJ, Ferreira FC “Extruded perfusion bioreactor as a customizable culture platform to study fluid shear stress stimuli in articular cartilage tissue engineered constructs” Oral Presentation by FC Ferreira Ferreira at 12th Symposium of the European Society of Biochemical Engineering Sciences, ESBES 2018. 9-12 September 2018, Lisbon, Portugal 43- Silva JC, Han X, Mikael P, Xia K, Cabral JMS, Ferreira FC, Linhardt RJ “Glycosaminoglycan dissacharides changes during chondrogenic differentiation of human bone marrow/synovial-derived mesenchymal stem cells under different oxygen tensions” Poster Presentation at EORS 2018 – 26th Annual Meeting, 25-28 September 2018, Galway-Ireland 44- Silva JC, Carvalho MS, Udangawa RN, Moura CS, Cabral JMS, Ferreira FC, Vashishth D, Linhardt RJ “Extracellular matrix decorated porous polycaprolactone scaffolds for bone tissue engineering” Poster Presentation at EORS 2018 – 26th Annual Meeting, 25-28 September 2018, Galway-Ireland 45- Manjua AC, Portugal CAM, Ferreira FC “Control of the Angiogenesis Process using Magnetic Scaffolds” Poster Presentation at 12th Symposium of the European Society of Biochemical Engineering Sciences, ESBES 2018. 9-12 September 2018, Lisbon, Portugal 46- Garrudo FFF, Chapman C, Undagawa RN, Silva JCF, Hoffman P, Mikael PE, Rodrigues C, Cabral JMS, Morgado JC, Ferreira FC, Linhardt RJ “Conductive PCL-PANI fibers for Neural Tissue Regeneration” Poster Presentation at 2018 BMES annual meeting, 17-20 October, 2018, Atlanta, US 47- Bandeiras C, Koc JR, Ma Y, Samberg M, Finkelstein S, Ferreira FC, Cost Effectiveness Analysis of Allogeneic, Just-In-Time Expansion of Mesenchymal Stem Cells with PLUS™ Human Platelet Lysate for a Clinical Trial”, Poster Presentation by C. Bandeiras at International Society for Cell Therapy, ISCT2018, Montréal, Canada, May 2-5, 2018 48- Barbosa P, Ribeiro M, Garcia AB, Tavares J, Carmo-Fonseca M, Fonseca A. VETA: a framework to assess computational tools for predicting clinical significance of genetic variation. Intelligent Systems for Molecular Biology and European Conference on Computational Biology, Basel, Switzerland, July 21-25, 2019. (Poster Presentation). 49- Barbosa P. Predicting clinical significance of intronic variation in disease-causing genes. RNA Informatics, Wellcome Genome Campus, Hinxton, Cambridge, UK, September 9-11, 2019. (Oral Presentation). 50- Silva TP, Fernandes TG, Bekman E, Vaz SH, Rodrigues CAV, Hashimura Y, Jung S, Lee B, Carmo-Fonseca M, Cabral JMS. Large scale production of cerebellar organoids from human pluripotent stem cells using the novel Vertical-Wheel single-use bioreactors. 7th International Conference on Stem Cell Engineering 2019, Barcelona, Spain, December 11-13, 2019. (Poster Presentation). 51- Silva TP, Fernandes TG, Bekman E, Vaz SH, Rodrigues CAV, Hashimura Y, Jung S, Lee B, Carmo-Fonseca M, Cabral JMS. Scalable generation of cerebellar neurons from pluripotent stem cells. Advancing Manufacture of Cell and Gene Therapies VI, California, USA, January 27-31, 2019 (Poster Presentation). 52- Ribeiro M, Furtado M, Carvalho T, Martins S, Tavares J, Lopes L, Syrris P P, Akhtar M, Elliot P and Carmo-Fonseca M. An improved tissue engineering protocol to generate cardiomyocytes from patient iPSCs. Annual meeting of the ESC Working Group on Myocardial & Pericardial Diseases (M&PD 2019), Corunã, Spain, October 4-5, 2019 (Poster Presentation). 53- Raymundo A, Rosmaninho P, Santos DF, Ferreira RD, Silva SP, Ferreira AC, Sousa AE, Silva SL, Modulation of the common variable immunodeficiency (CVID) clinical and immunological profile by Helicobacter pylori infection and the underlying genetic landscape. 19th Biennial Meeting of the European Society for Immunodeficiencies ESID 2020 (online meeting), 14-17 October 2020 (ePoster) 54- Pedro Rosmaninho, Susana Paço, Miguel Ângelo-Dias, Ana Godinho-Santos, Yumie Tokunaga, Ana Serra-Caetano, Helena Nunes-Cabaço, Ana Espada Sousa, Alexandre ASF Raposo, The signature of human CD4 regulatory thymocytes and its modulation by the chromatin landscape, selected for oral presentation by Pedro Rosmaninho, ESID 2020 (online meeting due to pandemic); 14-17 October 2020 (oral presentation) 55- Alexandre ASF Raposo, Diogo Tomaz, Miguel Dias, Ana Godinho-Santos, Yumie Tokunaga, Ana Serra-Caetano, Helena Nunes-Cabaço, Ana E Sousa, Homeostasis of the Human Naive CD4 T Cells: Changes in Transcriptomes of Regulatory and Conventional Cells reaveal distinct Mechanisms of Maintenance Independent of Thymic output, selected for oral presentatin of e-Poster by Alexandre Raposo, ESID 2019, Brussels, Belgium, September 18-21, 2019. 56- Alexandre ASF Raposo, Diogo Tomaz, Miguel Dias, Ana Godinho-Santos, Yumie Tokunaga, Ana Serra-Caetano, Helena Nunes-Cabaço, Ana E Sousa, Homeostasis of the Human Naive CD4 T Cells: Changes in Transcriptomes of Regulatory and Conventional Cells reaveal distinct Mechanisms of Maintenance Independent of Thymic output, selected for oral presentation of e-Poster by Alexandre Raposo, Focused Meeting of the European Society for Immunodeficiency: Malignancy and PID, ESID 2019, Brussels, Belgium, September 18-21, 2019. 57- Rosmaninho P., Ferreira R., Silva S., Cavadas B., Pereira L. , Câmara R., Faria E. , Regateiro F., Hammarström L., Raposo A.A.S.F., Sousa A.E., Silva S.L., Genome-wide study of patients with primary antibody deficiency and gastric carcinoma, ePoster, Focused Meeting of the European Society for Immunodeficiency: Malignancy and PID, ESID 2019, Brussels, Belgium, September 18-21, 2019 58- Duarte Ferreira R, Rosmaninho P, Silva SP, Raposo A, Ferreira C, Sousa AE, Silva SL. Synchronous gastric and hepatocelular carcinomas in a patient with primary antibody deficiency. Focused Meeting of the European Society for Immunodeficiency: Malignancy and PID, ESID 2019, Brussels, Belgium, September 18-21, 2019. (Selected Abstract for E-Poster Session Presentation). 59- Patrícia Corredeira, Patrícia Alves, Gisela Gordino, Sara Pereira, Julie Ribot, Pedro Andrade, Leonor Bruçó, Cristiana Pinheiro, Sandra Casimiro, Marta Martins, André Mansinho, Leonor Ribeiro, Isabel Fernandes, Inês Vendrell, Conceição Pinto, Maria Rita Dionísio, Rita Sousa, Bruno Silva-Santos, Luís Costa, “T cell profiling in metastatic breast cancer reveals a subtype independent immunosuppressive state” – I ASEICA-ASPIC International Meeting, Salamanca, Spain, September 12-13, 2019 60- Silva-Santos B. Delta One T cells: development of a novel cellular immunotherapy for cancer. First Joint Meeting of the Spanish and Portuguese Societies for Oncology Research, Salamanca, Spain, September 12-13, 2019. 61- Ana Rita Gomes, Tiago G Fernandes, Sandra H Vaz, Teresa P Silva, Evguenia Bekman, Sara Xapelli, Ana M Sebastião, Joaquim MS Cabral and Maria Margarida Diogo, “Engineering of Human Forebrain Organoids from Human Induced Pluripotent Stem Cells for Modeling of Rett Syndrome (RTT)”, 7th International Conference on Stem Cell Engineering 2019, Barcelona, Spain, December 11-13, 2019. 62- Pereira MJ, Ramalhete L, Aleixo S, Lobato da Silva C, Cabral JMS, Calado CRC and Fernandes-Platzgummer A. “Evaluating the impact of culture conditions on human mesenchymal stem/stromal cell derived exosomes through FTIR microscopy”, Advancing Manufacture of Cell and Gene Therapies VI, San Diego, USA, 2019. 63- Pereira MJ, Ramalhete L, Aleixo S, Lobato da Silva C, Cabral JMS, Calado CRC and Fernandes-Platzgummer A. “Evaluating the impact of culture conditions on human mesenchymal stem/stromal cell derived exosomes through FTIR microscopy”, Engineering Society for Animal Cell Technology 2019, Copenhagen, Denmark. 64- Fuzeta MA, Oliveira FD, Costa AC, Fernandes-Platzgummer A, Bernardes N, Gaspar D, Cabral JMS, Lobato da Silva C. Manufacturing Human Mesenchymal Stem/Stromal Cell (MSC)-Derived Extracellular Vesicles in Vertical-Wheel Bioreactors for Cancer Therapy. EACR conference on Nanotechnology in Cancer. Cambridge, United Kingdom, 2019. 65- Fuzeta MA, Oliveira FD, Costa AC, Fernandes-Platzgummer A, Jung S, Tseng RJ , Milligan W, Lee B, Bernardes N, Gaspar D, Cabral JMS, Lobato da Silva C. (2020), Scalable Production of Human Mesenchymal Stromal Cell (MSC)-Derived Extracellular Vesicles in Microcarrier-based Bioreactors under Xeno(geneic)-free Conditions. International Society for Cell and Gene Therapy Meeting 2020. Paris, France. 66- Soraia Lobo-Martins, Patrícia Corredeira, Patrícia Borges Alves, Marília Antunes, Ângela Rodrigues, António Quintela, Pedro Filipe, Leonor Ribeiro, Rita Teixeira de Sousa,Conceição Pinto, Catarina Abreu, Gisela Gordino, Julie Ribot, Karine Serre, Marta Martins, Ana Cavaco, Sandra Casimiro, Bruno Silva-Santos and Luís Costa, “Immune cell populations in peripheral blood of metastatic breast cancer patients under CDK4/6 inhibitors”- San Antonio Breast Cancer Symposium, December 8-11, 2020 67- da Silva CL, “Scalable manufacturing of MSC in three different bioreactor systems using hPL supplements” (virtual presentation), International Society of Cellular Therapy (ISCT) Annual Meeting, Paris (2020) 68- Cunha RMS, Vargas EJ, Pires FF, Calado CRC, Cabral JMS, da Silva CL, Fernandes-Platzgummer AM. Development of scalable processes to produce therapeutic mesenchymal stromal cell derived extracellular vesicles and their characterization. ISEV2020 Annual Meeting (virtual), 2020. 69- Ana Fernandes-Platzgummer, Sara Rosa, Ricardo Silva, Raquel MS Cunha, Miguel Fuzeta, Carla CCR Carvalho, Cecília Calado, Joaquim MS Cabral, Ana Azevedo, Cláudia Lobato da Silva. Scaling-up the manufacturing of well-characterized mesenchymal stromal cell-derived extracellular vesicles for biomedical applications. ISEV2020 Annual Meeting (virtual), 2020. 70- Garrudo FFF, Sousa M, Pires F, Ferreira Q, Chapman C, Hoffman P, Udangawa RN, Silva JC, Sordini L, Ferreira FA, Nogueira D, Filippone G, Rodrigues CA, Mikael P, Cabral JMS, Morgado J, Linhardt RJ, FFerreira FC, “The Dual Role of Electricity on Scaffolds: Preparation and Applications”. Keynote oral presention by Frederico Ferreira, Polymer Connect – Polymer Science and Composite Materials Conference, Sana Malhoa Hotel Lisbon, Portugal, February 26-28, 2020 71- Silva JS, Carvalho MS, Udangawa RN, Moura CS, Cabral JMS, da Silva CL, Ferreira FC, Vashishth D, Linhardt RJ, “Enhancing synthetic scaffolds biological performance and osteoinductive properties using stem cell-derived extracellular matrix”. Oral presentation by João Silva, Polymer Connect – Polymer Science and Composite Materials Conference, Sana Malhoa Hotel Lisbon, Portugal, February 26-28, 2020 72- Bak-Gordon P, Carvalho C, Custódio N, Carmo-Fonseca M. Characterizing the impact of pathogenic BRCA mutations on tissue-specific gene expression and pre-mRNA splicing. ESMO Breast Cancer Virtual Meeting. May 23-24, 2020. (Poster presentation). 73- Galvão B, Alves-Vale C, Silvestre AR, Nunes P, Carmo-Fonseca M, Custódio N. Patient-derived ovarian cancer organoids for modeling drug response. EMBO Symposium on Organoids: Modelling Organ Development and Disease in 3D Culture. Virtual. October 21-24, 2020. (Poster presentation). 74- Silva T P, da Rocha ST, Milagre I, Pereira C, Cabral JMS, Carmo-Fonseca, M. iPSC-derived mammary organoids as a model to study the onset of malignant transformation triggered by BRCA mutations. EMBO Symposium on Organoids: Modelling Organ Development and Disease in 3D Culture. Virtual. October 21-24, 2020. (Poster presentation). 75- Silveira C, Sousa AC, Corredeira P, Martins M, Sousa AR, Da Cruz Paula A, Selenica P, Brown DN, Golkaram M, Kaplan S, Zhang S, Liu L, Weigelt B, Reis-Filho JS, Costa L, Carmo-Fonseca M. Liquid biopsy detects therapy response in advanced breast cancer. EACR Virtual Conference on Liquid Biopsies. November 18-19, 2020. (Poster presentation). 76- Silva TP, da Rocha ST, Milagre I, Pereira C, Cabral JMS, Carmo-Fonseca M. iPSC-derived mammary organoids as a model to study the onset of malignant transformation triggered by BRCA mutations. Organoids With]Out[ Borders, Online Symposium, November 23, 2020. (Oral presentation). In national events1- Rodrigues CAV, Silva TP, Fernandes TG, Hashimura Y, Wesselschmidt R, Diogo MM, Lee B, Cabral JMS, “Scalable Expansion Of Human Induced Pluripotent Cells On Microcarriers Using Single-Use Vertical-Wheel Bioreactors”, 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Covilhã, Portugal, October 12-14, 2017. 2- de Sousa Pinto D, Ahsan T, Cabral JMS, da Silva CL, “Highlighting the Superior In Vitro Angiogenic Potential of Human Umbilical Cord Matrix-Derived Mesenchymal Stem/Stromal Cells Cultured Under Dynamic Conditions”, 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Covilhã, Portugal, October 12-14, 2017. 3- Silva, T.P., Bekman, E., Fernandes, T.G., Rodrigues, C.A.V., Diogo, M.M., Cabral, J.M.S., Carmo-Fonseca, M., “Cerebellar differentiation and maturation from Human Induced Pluripotent Stem Cells”, 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Covilhã, Portugal, October 12-14, 2017. 4- Gonçalves Rodrigo , Ribeiro M. , Martins S., Carvalho T., Carmo-Fonseca M. “Analysis of alternative splicing in hiPSC derived cardiomyocytes”, 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Covilhã, Portugal, 12-14 Oct, 2017. 5- Ribeiro, M., Tavares J., Garcia B., Carmo-Fonseca M. ”Discriminating power of computational tools for genetic diagnosis of hypertrophic cardiomyopathy”, Poster presentation at 21ª reunião anual da Sociedade Portuguesa de Genética Humana, Caparica, Portugal, 16-18 Nov, 2017. 6- Silva, T.P., Bekman, E., Fernandes, T.G., Rodrigues, C.A.V., Diogo, M.M., Cabral, J.M.S., Carmo-Fonseca, M., “Cerebellar differentiation and maturation from Human Induced Pluripotent Stem Cells”, PhD Open Days, Lisbon, Portugal, April 5-6, 2017. 7- Silveira C, “Precision Oncology in Breast Cancer”, 4ª Reunião de Utilizadores de Plataformas de NGS, Porto, Portugal, 2 October 2017. 8- Costa, L, “Liquid Biopsies in Clinical Oncology: how many dimensions and how much dynamics?” Proc. of Porto Cancer Meeting, Porto, May 2017 (invited speaker) 9-Carmo-Fonseca, M. Stem cells in heart failure. Hipertensão arterial e insuficiência cardíaca – estado da arte, Universidade de Lisboa, Portugal. 6 January 2017. 10- Carmo-Fonseca, M. Hearts-on-a-chip. “Leading the Heart” meeting organized by Bayer. Lisboa, Portugal. 25 March 2017. 11- Carmo-Fonseca, M. Novel molecular technologies for hematological malignancies. “Leaping Forward” international clinical congress. Lisboa, Portugal. 13 May 2017. 12- Carmo-Fonseca, M. Uma viagem pela biologia do cancro do pulmão. Astrazeneca Lung Cancer Summit 2017. Lisboa, Portugal. 20 May 2017. 13- Carmo-Fonseca, M. Medicina de precisão em oncologia: desafios futuros. Lição Ducla Soares, Reunião Anual da Sociedade Portuguesa de Hematologia. Vila Moura, Portugal. 18 November 2017. 14- Bernardes de Jesus B, Marinho SP, Sousa-Franco A, Alves-Vale C, Carvalho T, Carmo-Fonseca M. Silencing the long non-coding RNA antisense to Zeb2 facilitates reprogramming of aged fibroblasts and safeguards stem cell pluripotency Poster presented by Bruno Bernardes de Jesus at the Physiology: from development to disease, Champalimaud Research Center, Lisbon, 9-11 October 2017. 15- Ângelo-Dias M, Godinho-Santos A, Tokunaga Y, Serra-Caetano A, Nunes-Cabaço H, Sousa AE, Raposo AASF. Uncovering the regulatory T cell transcriptional signature in the human thymus. XLIV Meeting of the Portuguese Society for Immunology (SPI), Lisbon, 27-29 June 2018 (poster) 16- Varandas AC, Silva SP, Barbosa RR, Serra-Caetano A Barbosa MP, Sousa AE Silva SL. Autoimunidade e linfoproliferação: fenotipos distintos ou progressão da Imunodeficiência Comum Variável? Meeting of the Portuguese Society for Allergology and Clinical Immunology. Figueira da Foz, 28-30 September 2018 (oral presentation) 17- Di Lorenzo B, Simões A, Caiado F, Tieppo P, Ravens S, Correia DV, Carvalho T, Gomes Da Silva M, Norell H, Déchanet-Merville J, Prinz I, Vermijlen D, Silva-Santos B. Cytotoxic targeting of Acute Myeloid Leukemia by highly polyclonal Delta One T (DOT) cells. XLIV Annual Meeting of the Portuguese Society for Immunology, Lisboa, 27-29 de junho de 2018. (Apresentação em póster) 18- Di Lorenzo B, Simões A, Caiado F, Tieppo P, Ravens S, Correia DV, Carvalho T, Gomes Da Silva M, Norell H, Déchanet-Merville J, Prinz I, Vermijlen D, Silva-Santos B. Cytotoxic targeting of Acute Myeloid Leukemia by highly polyclonal Delta One T (DOT) cells. MIT-Portugal conference, Lisboa. 1 de outubro de 2018 (Apresentação em póster) 19- Pimenta DS, Almeida AG, Marto JP, Inacio, Nascimento PA, Baptista MV, Pinho e Melo T, Ferro JM, Fonseca AC, “Miocardiopatias em doentes adultos com AVC isquémico: um estudo de ressonância magnática cardíaca” Congresso de Neurologia 2018, Porto, Portugal, Novembro 15-17, 2018 20- Filipe Cortes-Figueiredo, Filipa S. Carvalho, René M. Gieß, Judith Bellmann-Strobl, Vanessa A. Morais. Unravelling longitudinal mitochondrial DNA mutations in Multiple Sclerosis: association with disease activity and progression. 2nd Annual NeurULisboa Meeting and Retreat, March 1- 2 2018, Lisbon, Portugal 21- Filipe Cortes-Figueiredo, Filipa S. Carvalho, René M. Gieß, Judith Bellmann-Strobl, Vanessa A. Morais. Nuclear and mitochondria instability in health and cancer – Scientific Symposium _ Unravelling longitudinal mitochondrial DNA mutations in Multiple Sclerosis. Montargil, Portugal, July 3 – 5 2018. 22- Filipe Cortes-Figueiredo, Filipa S. Carvalho, René M. Gieß, Judith Bellmann-Strobl, Vanessa A. Morais. Mitochondrial DNA mutations in Multiple Sclerosis: what is the relationship between mitochondrial genotype and disease triggering and progression? 4th PhD Students Meeting of the Mind-Brain College of the Universidade de Lisboa, November 14 – 15 2018, Lisbon, Portugal 23- Filipe Cortes-Figueiredo, Filipa S. Carvalho, René M. Gieß, Judith Bellmann-Strobl, Vanessa A. Morais, Friedemann Paul. Unravelling longitudinal mitochondrial DNA mutations in Multiple Sclerosis: association with disease activity and progression. SynaNet – 2nd Annual Scientific Meeting, January 17 – 18 2018, Lisbon, Portugal 24- Filipa S Carvalho, Filipe Cortes-Figueiredo, Ana C Fonseca, Sofia Galego, José M Ferro, Vanessa A Morais. Mitochondrial DNA mutations in stroke patients- a highway to a Precise Medicine. MitoPorto Internatioanl Symposium, July 13, 2018, Porto, Portugal 25- Filipe Cortes-Figueiredo, Filipa S. Carvalho, René M. Gieß, Judith Bellmann-Strobl, Friedemann Paul, Vanessa A. Morais. Multiple Sclerosis and mitochondria: a longitudinal cell-specific approach to mitochondrial DNA mutations. MitoPorto Internatioanl Symposium, July 13, 2018, Porto, Portugal 26- Silva JC, Moura CS, Borrecho G, Matos APA, Cabral JMS, Linhardt RJ, Ferreira FC, “Extruded scaffolds and perfusion bioreactors to study fluid shear stress stimuli in articular cartilage tissue engineered constructs”, Oral invited Presentation on national Workshop “Soft Matter in Biomedicine”, Invited presentation, Faculty of Sciences, Universidade de Lisboa, Lisboa, 12 October 2018, Lisbon, Portugal 27- Bruno Silva-Santos. Delta One T cells: towards the development of a novel immunotherapy for cancer. Porto Cancer Meeting. Porto, 27 de abril de 2018 (Apresentação oral por convite) 28- Gordino G., Pereira S., Gomes A.Q., Silva-Santos B., and Ribot J.C., miR-181a negatively regulates human gamma-delta T cell differentiation into anti-tumor effectors, XLIV Annual Meeting of the Portuguese Society for Immunology, Lisbon, June 27-29, 2018 (Poster Presentation). 29- da Silva CL, “Stem Cells and Future in Clinical Practice”, Gastro Expert Meeting’19 (3rd Edition), Porto (2019) 30- Bak-Gordon P, Luís R, Carmo-Fonseca M. Mining single-cell transcriptomic data for clues on tissue-specific expression of BRCA genes. RNA meeting ptRNA, Porto, Portugal, January 24-25, 2019. (Poster Presentation). 31- Carvalho C, Custódio N, Dias P, Porto B, Sousa AB, Carmo-Fonseca M. A BRCA2 intronic variant of uncertain significance alters pre-mRNA splicing. 23rd Annual Meeting of the Portuguese Society of Human Genetics, Coimbra, Portugal, November 14-16, 2019. (Poster Presentation). 32- Alexandre ASF Raposo, Miguel Ângelo-Dias, Diogo Tomaz, Ana Godinho-Santos, Yumie Tokunaga, Ana Serra-Caetano, Helena Nunes-Cabaço, Ana E Sousa. Monitoring human T-cell homeostasis: identification of different mechanisms of maintenance of regulatory and conventional naïve compartments. First Symposium of the national consortium “GenomePT”, CIBIO-InBIO, Vairão, Portugal, May 10th, 2019 (oral presentation) 33- Rosmaninho P, Raposo AASF, Abolhassani H, Hammarström L, Sousa AE, Silva SL. Mining the multigenic landscape underlying Common Variable Immunodeficiency Disorders. First Symposium of the national consortium “GenomePT”, CIBIO-InBIO, Vairão, Portugal, May 10th, 2019 (poster) 34- Varandas C, Silva SP, Barbosa RR, Serra-Caetano A, Barbosa MP, Sousa AE, Silva SL. Autoimmunity and lymphoproliferation: different or converging phenotypes in common variable immunodeficiencies?. EAACI Congress 2019, Lisboa, 1-5 june, 2019 (oral presentation) 35- Silva-Santos B. Gamma-delta T cells: pleiotropic roles and therapeutic potential. Cancer Immunotherapy Workshop, Champalimaud Centre for the Unknown, Lisbon, Portugal, March 27-29, 2019. 36- Silva-Santos B. Delta One T cells: development of a novel cellular immunotherapy for cancer. Annual Meeting of the Portuguese Society for Stem Cells and Cellular Therapies, Lisbon, Portugal, October 11, 2019. 37- Gordino G, Costa-Pereira SA, Gomes AQ, Silva-Santos B, Ribot JC. miR-181a negatively regulates human γδ T cell differentiation into anti-tumor effectors. Champalimaud Research Symposium 2019, Lisbon, Portugal, October 8-10, 2019. (Poster Presentation). 38- Fuzeta MA, Oliveira FD, Costa AC, Fernandes-Platzgummer A, Bernardes N, Gaspar D, Cabral JMS, Lobato da Silva C., Scalable Production of Human Mesenchymal Stem/Stromal Cell (MSC)-Derived Extracellular Vesicles in Vertical-Wheel Bioreactors. 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies. Lisbon, Portugal, 2019. 39- Silva JC, Moura CS, da Silva CL, Cabral JMS, Linhardt RJ, Ferreira FC, “Extruded perfusion bioreactor: a custom-made platform to enhance the chondrogenic differentiation of mesenchymal stem/stromal cells in 3D porous scaffolds”. Poster Presentation at 3rd Stem Cell Community Day 2019, Lisbon, Portugal, 21st November 2019. 40- Garrudo F, Mikael P, Udangawa R, Chapman C, Hoffman P, Silva J, Rodrigues C, Cabral J, Morgado J, Ferreira F, Linhardt R, HARNESSING ELECTRICITY FOR NEURAL STEM CELLS, Poster presentation at Meeting of the Portuguese Society for Neurosciences SPN, Lisboa , May 30th 2019. 41- Carmo-Fonseca M. As bases moleculares da terapia génica. Congresso da Sociedade Portuguesa de Estudos de Doenças Neuromusculares, Virtual, October 23, 2020. 42- Carmo-Fonseca M. As bases moleculares da terapia génica. Congresso APFH, Virtual, November 16, 2020. 43- Carmo-Fonseca M. Human genome sequencing and cancer: 20 years of history. 17º Congresso Nacional de Oncologia, Virtual, November 20-21, 2020. 44- Carmo-Fonseca M. Os novos desafios da medicina de precisão. 8º Congresso Internacional dos Hospitais, Virtual, November 26-27, 2020. 45- Silva TP. Organoids as Models for Cerebellar Development. Brain Organoids Virtual Seminar, StemCellTM Technologies, June 8, 2020. 46- Carvalho, C, Custódio, N, Dias, P, Porto, B, Sousa, AB and Carmo-Fonseca, M. A biallelic intronic variant in the BRCA2 gene affects splicing and DNA damage repair. International meeting of the Portuguese Society of Genetics. Faro, Portugal. January 23-24, 2020. (Poster presentation) 47- Furtado M, Martins S, Carvalho T, Ribeiro M, Proença J, Barreto V, and Carmo-Fonseca M. Gene edited iPSC-derived cardiomyocytes reveal RNA splicing defects in Hypertrophic Cardiomyopathy. 24th Annual Meeting of Sociedade Portuguesa de Genética Humana, Virtual. November 20, 2020. (Oral presentation). 48- Bak-Gordon P, Carvalho C, Custódio N, Carmo-Fonseca M. Looking beyond DNA II: Screening for mRNA biomarkers of response to PARP inhibition. Dia da Investigação – 9ºEdição, GAPIC, Faculdade de Medicina da Universidade de Lisboa, Portugal. December 9, 2020. (Poster presentation). 49- Grilo M, Antunes R, Custódio N, Why does BRCA loss of function predisposes to tumors mainly in estrogen-related tissues? Dia da Investigação – 9ºEdição, GAPIC, Faculdade de Medicina da Universidade de Lisboa, Portugal. December 9, 2020. (Poster presentation). 50- Catarina Ribeiro, Carvalho C, Carmo-Fonseca M. Qual o mecanismo pelo qual o lncRNA PCAT-1 afeta a expressão de BRCA2? Dia da Investigação – 9ºEdição, GAPIC, Faculdade de Medicina da Universidade de Lisboa, Portugal. December 9, 2020. (Poster presentation) 51- Beatriz Anjo Lima, Carvalho C, Carmo-Fonseca M. Modulação de splicing em doentes portadores de mutação no gene BRCA2: potencial terapêutico. Dia da Investigação – 9ºEdição, GAPIC, Faculdade de Medicina da Universidade de Lisboa, Portugal. December 9, 2020. (Poster presentation) Reports– António Higgs. Precise Stroke Tool Report. INESC-ID Oct 2017. Event organization1- Cláudia Lobato da Silva, Scientific Committee, 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Covilhã, Portugal, October 12-14, 2017. 2- Joaquim MS Cabral, Organizing Committee, Scale-up and Manufacturing of Cell-based Therapies V, San Diego, USA, January 15-19, 2017. 3- Joaquim MS Cabral, Scientific Committee, 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Covilhã, Portugal, October 12-14, 2017. 4- Alexandre P Francisco, member of the Local Organizing Committee for 5- Bruno Silva-Santos e Haakan Norell, organizadores da “Immunotherapy Workshop” na Reunião Anual da Sociedade Portuguesa de Hematologia, Vilamoura, 16 de novembro de 2017. 6- Silva SL, Sousa AE. 18th Biennial Meeting of the European Society for Immunodeficiencies (ESID 2018), Lisbon, Portugal, 24-27 October 2018 7- Sousa AE. XLIV Meeting of the Portuguese Society for Immunology (SPI 2018), Lisbon, Portugal, 27-29 June 2018 8- Bruno Silva-Santos, co-organizor do XLIV Annual Meeting of the Portuguese Society of Immunology. Instituto de Medicina Molecular, Lisboa (Portugal), 27-29 de junho de 2018. 9- Ferro JM. Organizor and Chair “Focused workshop – Precision Medicine in Stroke” , 4º European Congress of the European Academy of Neurology, Lisbon, Portugal, June 16-19, 2018 10- Carmo-Fonseca M. Organizer. 2nd COST Action CardioRNA, Instituto de Medicina Molecular João Lobo Antunes, Lisbon, Portugal, February 13-15, 2019. 11- Carmo-Fonseca M. Organizer. First RNA in Disease (RiboMed) meeting, Hotel Riviera, Carcavelos, Portugal, October 14-16, 2019. 12- Carmo-Fonseca M. Organizer. Seminar entitled “Regulation of alternative splicing by transcription elongation and the therapy of an hereditary disease” by Professor Alberto Kornblihtt (University of Buenos Aires, Argentina) Instituto de Medicina Molecular João Lobo Antunes, Lisbon, Portugal, September 4, 2019. 13- Carmo-Fonseca M. Organizer. Seminar entitled “Dysregulation of alternative splicing in cancer and its modulation for therapy” by Professor Rotem Karni (Hebrew University-Hadassah Medical School, Israel) Instituto de Medicina Molecular João Lobo Antunes, Lisbon, Portugal, December 12, 2019. |
ThesisPhD thesis1- Márcia Andreia Faria da Mata, “Stem cell engineering approaches towards angiogenic cell therapy for ischemic diseases”, PhD in Biotechnology and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Cláudia Lobato da Silva (Supervisor)/Marco Costa (Co-Supervisor) (May 2018) 2- Miriam Calado Amores de Sousa, “Ex-Vivo Culture of Neural Stem Cells in Nanofiber Scaffolds: Cellular Organization and Dynamic Systems”, PhD in Biotechnology and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Frederico Castelo Alves Ferreira (October 2018) 3- Diogo de Sousa Pinto, “Towards the development of a mesenchymal stem/stromal cell product with enhanced therapeutic features for myocardial infarction”, PhD in Bioengineering (MIT-Portugal Program), Instituto Superior Técnico, Universidade de Lisboa, Cláudia Lobato da Silva (Supervisor)/António Fiarresga (Co-Supervisor) (November 2018) 4- Raquel Medina dos Santos Cunha, “Towards the development of potency assays and 3D inflammation models to evaluate the regenerative potential of Mesenchymal Stem/Stromal Cell (MSC) and MSC-derived products”, PhD in Bioengineering (MIT-Portugal Program), Instituto Superior Técnico, Universidade de Lisboa, Cláudia Lobato da Silva (Supervisor)/António Fiarresga (Co-Supervisor)/Jeffrey Karp (Co-Supervisor) (November 2018) 5- Teresa Maria Pereira da Silva. “Novel bioengineering strategies for modelling cerebelar ataxias”. Dissertação de Doutoramento em Bioengenharia, Instituto Superior Técnico da Universidade de Lisboa. 26 Outubro 2018. Orientador: Maria Carmo-Fonseca. Co-orientador: Joaquim Cabral. 6- Joana Gesta, “Expansion and in-depth characterization of antigen-specific regulatory T cells in vitro for subsequent clinical translation”, PhD in Bioengineering: Cell Therapies and Regenerative Medicine, Instituto Superior Técnico, Universidade de Lisboa. Orientador: João F. Lacerda, IMM. Co-orientadores: Cláudia Lobato da Silva /Rita Azevedo) (2019) 7- Biagio Di Lorenzo, “Characterization of the gamma-delta1+ T Cell Receptor repertoire during early and adult human life: implication of clonal diversity for cancer immunotherapy”, PhD in Bioengineering, MIT-Portugal Program, Instituto Superior Técnico, Universidade de Lisboa. Orientador: Bruno Silva-Santos. Co-orientador: Cláudia Lobato da Silva. (2019) 8- Joana Serra, “Ex-vivo gene therapy to improve the regenerative features of human mesenchymal stem/stromal cells (MSC) in a model of limb ischemia”, PhD in Bioengineering: Cell Therapies and Regenerative Medicine, Instituto Superior Técnico, Universidade de Lisboa Orientador: Miguel Prazeres. Co-orientadores: Cláudia Lobato da Silva/Sang W. Han. (2019) 9- Siddhi Bianca Camila Lama, Development of a Biocompatible, Electroconductive, Elastomeric Construct for Use as a Somatosensory System Microenvironment, (9 December 2019), PhD Student in Bioengineering, PD/BD/52338/2013 (MIT Portugal Program). Supervisor: F.C. Ferreira (IBB-IST), Co-supervisors: Jorge Martins (IST), Ann Rajnicek (Institute of Medical Sciences, University of Aberdeen); with collaboration of Carlos Alemán and Eloi Pineda (Barcelona Research Center for Multiscale Science and Engineering, Universitat Politècnica de Catalunya) 10- Cátia Filipa Medina Bandeiras, TESSEE – Tool for Early Stem Cells Economic Evaluation (8 November 2019), PhD Student in Bioengineering, PD/BD/105868/2014 (MIT Portugal Program). Supervisor; F.C. Ferreira (IBB-IST), Prof. Stan Neil Finkelstein (MIT) 11- João Carlos Fernandes da Silva, Bioengineering strategies towards the in vitro fabrication of hierarchical and biomimetic cartilage constructs, (21 March 2019), PhD Student in Bioengineering: Cell Therapies and Regenerative, SFRH/BD/105771/2014 (FCT PhD Programme). Supervisor: F.C. Ferreira (IBB-IST), Co-supervisors: Professor Robert J. Linhardt (RPI) 12- Marta de Jesus Ribeiro, 22/05/2020 “Developing cellular models for Hypertrophic Cardiomyopathy”, PhD in Bioenginnering, Institute of Molecular Medicine and Biosciences and Biotechnology Institute, University of Lisbon, Portugal. Supervisor: Maria-Carmo Fonseca. Co-Supervisors: Sandra Martins e Margarida Diogo. MSc thesis1- André Lopes Rodrigues, “Scalable expansion and harvesting of hiPSCs using dissolvable microcarriers, Tese de Mestrado em Biotecnologia”, Instituto Superior Técnico, Universidade de Lisboa, Novembro de 2017. Orientadores: Carlos André Vitorino Rodrigues e Maria Margarida Fonseca Rodrigues Diogo. 2- Ana Filipa Potes Semião, “Strategies for Chondrogenic Differentiation of Human Induced Pluripotent Stem Cells”, Tese de Mestrado em Engenharia Biológica, Instituto Superior Técnico, Universidade de Lisboa, Novembro 2017. Orientadores: Carlos André Vitorino Rodrigues e Maria Margarida Fonseca Rodrigues Diogo. 3- Maria Marques Adegas Bairrão Henriques, “Development of tools to study human hair follicle biology in vitro – focus on hair follicle stem cells and their potential application in Vitiligo therapy”, Tese de Mestrado em Engenharia Biomédica, Instituto Superior Técnico, Universidade de Lisboa, Novembro 2017. Orientadores: Paulo Fililipe (IMM), João Ferreira (IMM) & Cláudia Lobato da Silva (IST). 4- Rodrigo Paiva Gonçalves, “Assessment of hiPSC derived cardiomyocytes maturation in extended culture by analysis of alternative splicing expression patterns”, Molecular Biology and Genetics, Faculdade de Ciências da Universidade de Lisboa, Lisbon, Portugal (31 Oct, 2017). 1)Catarina Alves-Vale, “Unravelling the role of the long noncoding RNA NORAD in breast cancer”, Mestrado Integrado em Medicina, Faculdade de Medicina da Universidade de Lisboa (27 July, 2017). 5- Ana Guerreiro “A disease modelling approach for Angelman syndrome based on neuronal differentiation of human patient-derived iPSCs”. Master in Biological Engineering, Instituto Superior Técnico da Universidade de Lisboa. (18 valores) Supervisor: Simão T da Rocha; Co-supervisor: Tiago Fernandes. 2018 6- Maria Arez “Comprehensive Evaluation of Genomic Imprinting Stability in Mouse iPSCs”. Master in Molecular Genetics and Biomedicine, Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa. (19 valores). Supervisor: Simão T da Rocha; Co-supervisor: Bruno Bernardes de Jesus. 2018 7- Inês Godinho“The role of Meg3 lncRNA in imprinting and pluripotency” Master in Molecular Biology and Genetics, Faculdade de Ciências da Universidade de Lisboa. (18 valores) Supervisor: Simão T da Rocha. 2018 8- Inês Domingues Oliveira “Detection of BRAF V600E mutation in ctDNA by ddPCR: from laboratory to market”. Mestrado em Biotecnologia, Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa. Provas a 13 de Setembro 2018, aprovação com 18 valores. Supervisor: M. Carmo-Fonseca. Co-supervisor: Fernanda Llussá. 9- Ana Beatriz Nogueira Garcia “Variantes genéticas associadas à Miocardiopatía Hipertrófica – Interpretação do seu significado clínico”. Mestrado Integrado em Medicina, Faculdade de Medicina da Universidade de Lisboa. Provas a 23 de Julho 2018, Aprovada. Supervisor: M. Carmo-Fonseca. 10- Cristiana Morgado “Programmed DNA damage as a new tool to regulate gene activation” Mestrado em Biologia Molecular e Genética, Faculdade de Ciências da Universidade de Lisboa. (9 Outubro 2018). Supervisor: S. de Almeida 11- Miguel Angelo Simão Dias, Title: “Uncovering the regulatory T cell transcriptional signature in the human thymus”. Supervisor: Alexandre ASF Raposo. Co-Supervisor: Ana E. Sousa. Mestrado em Biologia Molecular e Celular da Universidade de Coimbra. 10th September 2018. 12- Margarida Correia, “Automatic Annotation of Unstructured Fields in Medical Databases”, Instituto Superior Técnico, Nov. 2018. 13- Silvia Gonella “Towards 3D in vitro models of Osteoarthritis” Master thesis in Biomedical Engineering, Politecnico di Milano, Supervisors: Sara Mantero, Frederico Castelo Alves Ferreira, Co-Supervisor Carlos Andre Vitorino Rodrigues. 2018 14- Laura Sordini “Assessing electrectically conductive polymers for the manufacture of substrates for neural stem cells cultures”, Master thesis in Biomedical Engineering, Politecnico di Milano, Supervisors: Sara Mantero, Frederico Castelo Alves Ferreira, Co-Supervisor Jorge Manuel Ferreira Morgado. 2018 15- Ana Sofia Borges, “Isolation and characterization of different cell types from lipoaspirates used for treating patients with alopecia”, Master in Biomedical Engineering, Supervisor Ana Fernandes-Platzgummer and Co-Supervisor Tiago Baptista Fernandes. 2018 16- Maria João Canha, ”Study the Influence of the culture conditions on therapeutic human mesenchymal stem/stromal cell-derived exosomes cargo through FTIR spectroscopy”, Master in Biologic Engineering, Supervisor Ana Fernandes-Platzgummer and Co-Supervisor Cecília Calado. 2018 17- Cristiana da Silva Ulpiano, “RNAi as a tool to inhibit the angiogenic potential of human Mesenchymal Stem/Stromal Cells in malignancy”, Master in Biotechnology, Supervisor Gabriel Monteiro and Co-Supervisor Cláudia Lobato da Silva. 2018 18- Pedro Manuel Mesquita Pereira, A Bioreactor for chondrocyte differentiation: design, modelling and prototyping, 6 Dec 2019, MSc in Biological Engineering (IST), Supervisor: F.C. Ferreira 19- Catarina Guerra Ferreira, 20/12/2019, Mammary organoids to study the functional impact of BRCA mutations, Mestrado em Ciências Biofarmacêuticas, Faculdade de Farmácia da Universidade de Lisboa (16 Valores). Supervisor: M. Carmo-Fonseca. 20- Miguel Francisco Cruz Romano Guedes, 18/12/2019, How the lncRNA Zeb2-NAT regulates the expression of Zeb2, Mestrado em Ciências Biofarmacêuticas, Faculdade de Farmácia da Universidade de Lisboa (16 Valores). Supervisor: Noélia Custódio. 21- Marta Isabel Brandão Furtado Furtado, 13/12/2019 “Developing gene-edited models to study mis-splicing in Hypertrophic Cardiomyopathy”, Master in Molecular Genetics and Biomedicine, Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa (19 Valores). Supervisor: Sandra Martins. Co-Supervisor: Teresa Carvalho. 22- Pedro Rodrigues dos Santos. “Classification of patients with Common Variable Immunodeficiency – different strategies”. Master Thesis – Mestrado Integrado em Medicina, FMUL, 29 July 2020 (Tutor Silva SL) 23- Cristiano Esteves, 18/12/2020, Instability of X-chromosome inactivation in female human iPSCs. Mestrado Integrado em Medicina. Faculdade de Medicina da Universidade de Lisboa. Supervisor: Simão Teixeira da Rocha. |